EPICSCORE: A Novel Approach to Quantifying Epistemic Uncertainty in Machine Learning

Sunday 23 March 2025


In the realm of machine learning, uncertainty is a constant companion. As algorithms strive to predict outcomes with increasing precision, they must also confront the limitations of their own knowledge and understanding. A new approach, dubbed EPICSCORE, aims to address this challenge by integrating epistemic uncertainty into conformal prediction.


Conformal prediction, in itself a powerful technique for generating reliable predictions, relies on the idea that a model’s confidence in its outputs should be directly proportional to its performance on unseen data. In other words, if a model is highly confident in its predictions, it should also perform well on new data. EPICSCORE takes this concept one step further by incorporating epistemic uncertainty, which reflects the degree of doubt or uncertainty that a model has about its own predictions.


The key innovation behind EPICSCORE lies in its ability to adaptively expand predictive intervals in regions where data is sparse or limited. This is achieved through the use of Bayesian techniques such as Gaussian Processes, Monte Carlo Dropout, and Bayesian Additive Regression Trees. By doing so, EPICSCORE can maintain compact intervals where data is abundant while still providing a more nuanced understanding of uncertainty in data-sparse areas.


The benefits of EPICSCORE are twofold. Firstly, it provides a model-agnostic approach that can be applied to any Bayesian model, making it a versatile tool for uncertainty quantification. Secondly, its distribution-free guarantees ensure that the predictive intervals constructed by EPICSCORE will have finite-sample marginal coverage, meaning they will contain the true outcome with high probability.


To evaluate the effectiveness of EPICSCORE, researchers conducted experiments on several datasets, including regression and classification problems. The results showed that EPICSCORE outperformed existing methods in terms of interval length and coverage, demonstrating its ability to balance precision and uncertainty.


In practice, EPICSCORE has far-reaching implications for fields such as healthcare, finance, and climate modeling, where uncertainty quantification is critical for informed decision-making. By providing a more accurate representation of uncertainty, EPICSCORE can help mitigate the risks associated with high-stakes predictions and enable data-driven decision making.


As machine learning continues to evolve, the need for robust and adaptive uncertainty quantification methods will only grow more pressing. With its ability to adaptively expand predictive intervals and provide distribution-free guarantees, EPICSCORE represents a significant step forward in this area, offering a powerful tool for researchers and practitioners alike.


Cite this article: “EPICSCORE: A Novel Approach to Quantifying Epistemic Uncertainty in Machine Learning”, The Science Archive, 2025.


Machine Learning, Uncertainty, Conformal Prediction, Epistemic Uncertainty, Gaussian Processes, Monte Carlo Dropout, Bayesian Additive Regression Trees, Predictive Intervals, Interval Length, Coverage


Reference: Luben M. C. Cabezas, Vagner S. Santos, Thiago R. Ramos, Rafael Izbicki, “Epistemic Uncertainty in Conformal Scores: A Unified Approach” (2025).


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