Simulating Biological Systems with Mathematical Models

Monday 03 March 2025


Researchers have been studying a complex mathematical phenomenon called gradient flows, which describe how systems change over time in response to external forces. In particular, they’ve been focusing on a type of gradient flow that occurs on a space called the Wasserstein space.


The Wasserstein space is a bit like a map that helps us understand how things move and change in different environments. It’s used to study everything from traffic flow to crowd behavior to chemical reactions. But what makes it really interesting is that it can also be used to describe complex biological systems, like cells and tissues.


In this new paper, scientists have developed a way to use the Wasserstein space to simulate how these biological systems change over time. They did this by creating a mathematical model that captures the essential features of gradient flows in one dimension.


One-dimensional gradient flows are often used to study simple systems, like a single particle moving through a potential energy landscape. But the new paper shows that this approach can be applied to much more complex systems, like cells and tissues.


The researchers used their model to simulate how cells move and interact with each other over time. They found that the model accurately predicted the behavior of real cells in certain situations, which is exciting because it could lead to better understanding of how diseases spread or how cancer develops.


The approach also has potential applications in fields like biomedicine and materials science. For example, it could be used to design new treatments for diseases or to create more efficient ways to deliver medicine.


The paper’s authors are excited about the possibilities their work opens up. They’re already working on extending their model to higher dimensions, which would allow them to study even more complex biological systems.


This research is a great example of how math can be used to understand and predict complex phenomena in biology. By developing new mathematical tools and techniques, scientists like these researchers are helping us better understand the world around us.


Cite this article: “Simulating Biological Systems with Mathematical Models”, The Science Archive, 2025.


Mathematics, Biology, Gradient Flows, Wasserstein Space, Mathematical Modeling, Simulation, Cell Movement, Tissue Interactions, Disease Spread, Cancer Development.


Reference: Rong Lei, “Convergence of a particle method for gradient flows on the $L^p$-Wasserstein space” (2025).


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