AVSim: A Cutting-Edge Simulation Framework for Understanding Disease Transmission Dynamics

Saturday 22 March 2025


The COVID-19 pandemic has brought attention to the importance of understanding disease transmission dynamics, particularly in urban areas where human mobility plays a significant role. A new simulation framework, called AVSim, aims to provide insights into airborne and vector-borne diseases by modeling complex real-world environments.


AVSim is an agent-based model that simulates entire cities, subdivisions, zones, and even individual households. By leveraging demographic data of the modeled geographical area, AVSim generates agent entities that accurately represent the population. The movement of these agents is modeled using a novel probability-based approach informed by real-world GPS data collected from 100 individuals across various occupational classes.


One of the key features of AVSim is its ability to simulate infections based on professional classes and supports a variety of analyses to study disease dynamics. For instance, the model can predict how different control measures, such as social distancing or mask-wearing, would affect the spread of disease in specific areas.


The simulation framework also takes into account various environmental factors that can influence disease transmission, including temperature, humidity, and wind direction. This allows researchers to investigate how these factors impact the spread of diseases like dengue fever.


To validate AVSim’s accuracy, the model was tested against real-world data from Sri Lanka, where it accurately predicted the spread of COVID-19 in different regions. The framework also demonstrated its ability to identify vulnerable agent groups and high-risk locations, providing valuable insights for policymakers and public health officials.


AVSim’s potential applications are vast, ranging from predicting the impact of new variants on disease transmission to informing vaccination strategies. By providing a more accurate understanding of how diseases spread, AVSim can help researchers develop targeted interventions that minimize societal and economic disruption.


The development of AVSim is an important step towards creating more effective public health policies. As urban populations continue to grow and diseases become increasingly complex, the need for sophisticated simulation frameworks like AVSim becomes even more pressing. By leveraging cutting-edge technology and real-world data, researchers can create more accurate models that help protect global health.


AVSim’s ability to simulate complex environments and predict disease transmission dynamics makes it an invaluable tool in the fight against infectious diseases. As the world continues to navigate the challenges posed by COVID-19 and other emerging threats, AVSim’s potential to provide actionable insights will only continue to grow.


Cite this article: “AVSim: A Cutting-Edge Simulation Framework for Understanding Disease Transmission Dynamics”, The Science Archive, 2025.


Covid-19, Disease Transmission Dynamics, Urban Areas, Simulation Framework, Agent-Based Model, Airborne Diseases, Vector-Borne Diseases, Public Health Policies, Infectious Diseases, Pandemic.


Reference: Pandula Thennakoon, Mario De Silva, M. Mahesha Viduranga, Sashini Liyanage, Roshan Godaliyadda, Mervyn Parakrama Ekanayake, Vijitha Herath, Anuruddhika Rathnayake, Ganga Thilakarathne, Janaka Ekanayake, et al., “AVSim — Realistic Simulation Framework for Airborne and Vector-Borne Disease Dynamics” (2025).


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