Unlocking the Secrets of Soft Matter with Optical Coherence Tomography

Tuesday 04 March 2025


Soft matter, a field that encompasses everything from ketchup to lubricants, has long been a challenge for scientists and engineers. The properties of these materials can be notoriously difficult to measure and understand, often requiring specialized equipment and techniques.


One tool that’s gained popularity in recent years is optical coherence tomography (OCT). Typically used in medical imaging, OCT uses low-coherence interferometry to capture high-resolution images of samples without damaging them. In the hands of researchers like Kasra Aminia and Cornelius Wittiga, OCT has become a powerful tool for studying soft matter.


Aminia and Wittiga’s work focuses on using OCT to visualize and analyze various soft matter systems, from biofilms to lubricants. By leveraging the technology’s ability to capture detailed images of samples in three dimensions, they’ve been able to gain new insights into the behavior of these complex materials.


One example of their work involves studying biofilms, communities of microorganisms that thrive on surfaces and can cause problems in everything from medical devices to industrial equipment. Using OCT, Aminia and Wittiga were able to visualize the structure and composition of these biofilms in unprecedented detail, revealing new information about how they form and interact with their environments.


Another area where OCT has proven useful is in the study of lubricants. By capturing images of lubricant droplets confined within tiny channels, researchers can gain a better understanding of how they behave under different conditions. This information can be used to develop more effective lubricants for applications like industrial machinery or biomedical devices.


One of the key challenges in working with soft matter is that many of these materials are highly sensitive to their environments and can change properties rapidly. OCT’s ability to capture high-resolution images quickly and accurately makes it an ideal tool for studying these systems in real-time.


Aminia and Wittiga have also developed a range of software tools to help researchers make the most of OCT data. These include algorithms for thresholding, which can be used to isolate specific features or phases within complex images, as well as techniques for processing Doppler-velocity data from OCT measurements.


The potential applications of OCT in soft matter research are vast and varied. From developing new medical devices to improving industrial processes, the technology has the potential to make a significant impact across a range of fields.


As researchers continue to push the boundaries of what’s possible with OCT, it will be exciting to see how this technology is applied in the years to come.


Cite this article: “Unlocking the Secrets of Soft Matter with Optical Coherence Tomography”, The Science Archive, 2025.


Soft Matter, Optical Coherence Tomography, Biofilms, Lubricants, Medical Imaging, Low-Coherence Interferometry, High-Resolution Images, Real-Time Analysis, Doppler-Velocity Data, Image Processing


Reference: Kasra Amini, Cornelius Wittig, Sofia Saoncella, Outi Tammisola, Fredrik Lundell, Shervin Bagheri, “Optical Coherence Tomography in Soft Matter” (2025).


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