Revolutionizing Medical Imaging with LUCAS: A Breakthrough Silicon Photomultiplier Readout ASIC

Thursday 20 March 2025


A new chip has been developed that could revolutionize medical imaging by providing faster and more accurate diagnoses. The silicon photomultiplier (SiPM) readout ASIC, dubbed LUCAS, is designed to be used in time-of-flight computed tomography (ToF-CT) applications.


In traditional CT scans, X-ray photons are emitted from a continuous source and detected on the opposite side of the body. However, this method has limitations due to scattering, which can introduce noise and artifacts into the images. ToF-CT, on the other hand, uses pulsed X-ray sources and detectors to create detailed anatomical images.


LUCAS is designed to overcome some of the challenges associated with ToF-CT by providing a low-power, ultra-low jitter ASIC that can accurately detect and time the pulses of X-rays emitted from the source. The chip features eight channels with integrated preamplifiers and comparators, allowing it to achieve high timing resolution while minimizing power consumption.


The development of LUCAS is significant because it could enable faster and more accurate diagnoses in a range of medical applications, including oncology and neurology. With its ability to provide detailed images of the body’s internal structures, ToF-CT has the potential to revolutionize the way doctors diagnose and treat diseases.


One of the key challenges associated with developing LUCAS was addressing the issue of parasitic capacitance, which can cause signal degradation and reduce the chip’s timing resolution. The designers overcame this challenge by using a novel preamplifier design that features low input impedance and current-mode operation.


The performance of LUCAS has been validated through experimental testing, with the chip achieving an impressive single photon time resolution (SPTR) of 201 picoseconds at just 3.2 milliwatts per channel. This level of performance is crucial for ToF-CT applications, where precise timing is essential for creating accurate images.


The development of LUCAS is a significant milestone in the field of medical imaging, and its potential applications are vast. The chip’s ability to provide high-quality images quickly and accurately could have a major impact on patient care, enabling doctors to diagnose and treat diseases more effectively.


Cite this article: “Revolutionizing Medical Imaging with LUCAS: A Breakthrough Silicon Photomultiplier Readout ASIC”, The Science Archive, 2025.


Medical Imaging, Ct Scans, Sipm, Readout Asic, Lucas, Tof-Ct, X-Ray Detection, Timing Resolution, Parasitic Capacitance, Single Photon Time Resolution.


Reference: Seyed Arash Katourani, “LUCAS: A CMOS-Based Fast Readout ASIC for Silicon Photomultipliers — Measurement and Performance Evaluation” (2025).


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